Alpha-Lipoic Acid with Biotin – 60 caps
Alpha-lipoic acid is an antioxidant used in Europe to promote liver and nerve health, and confer protective benefits against oxidative processes. Alpha-lipoic acid has been called the “universal” antioxidant because it boosts glutathione levels in cells already within a normal range and has potent antioxidant actions.
Research has strongly implicated cellular oxidative damage caused by free radicals. What makes alpha-lipoic acid so effective as an antioxidant is its ability to quench free radicals in both aqueous and lipid environments. This means that the antioxidant activity of alpha-lipoic acid is working in the extra-cellular fluid and also within the cell. It also has metal chelating ability, helping the body rid itself of accumulated ingested toxins.
Alpha-lipoic acid also is a cofactor for some of the key enzymes (alpha keto acid dehydrogenases) involved in generating energy from food and oxygen in mitochondria8-10 and thus plays a critical role in energy production within the cell’s mitochondria.
One of the most beneficial effects of alpha-lipoic acid is its ability to regenerate other essential antioxidants such as vitamins C and E, coenzyme Q10, and glutathione, and the activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx). The evidence is especially strong for the ability of DHLA (dihydrolipoic acid, a reduced form of alpha-lipoic acid) to recycle vitamin E. This is apparently achieved directly by quenching tocopherol radicals or indirectly by reducing vitamin C or increasing the levels of ubiquinol (a derivative of CoQ10) and glutathione, that, in turn, helps regenerate tissue levels of vitamin E.
In clinical studies to date with alpha-lipoic acid, there have been no reported serious adverse side effects, even at high doses.
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